BDBM50185839 9a-butyl-4-(furan-2-yl)-7-hydroxy-1,2,9,9a-tetrahydrofluoren-3-one::CHEMBL378675

SMILES CCCCC12Cc3cc(O)ccc3C1=C(c1ccco1)C(=O)CC2

InChI Key InChIKey=ZUMQFABIHNHCCM-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50185839   

TargetEstrogen receptor beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185839(9a-butyl-4-(furan-2-yl)-7-hydroxy-1,2,9,9a-tetrahy...)
Affinity DataIC50: 3.10nMAssay Description:Binding affinity to ERbeta by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185839(9a-butyl-4-(furan-2-yl)-7-hydroxy-1,2,9,9a-tetrahy...)
Affinity DataEC50:  5nMAssay Description:Activity at human ERbeta transfected in HEK293 cells assessed as transactivation of alkaline phosphatase reporter geneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185839(9a-butyl-4-(furan-2-yl)-7-hydroxy-1,2,9,9a-tetrahy...)
Affinity DataIC50: 196nMAssay Description:Binding affinity to ERalpha by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed