BDBM50185865 9a-butyl-7-hydroxy-3-oxo-2,3,9,9a-tetrahydro-1H-fluorene-4-carbonitrile::CHEMBL376986

SMILES CCCCC12Cc3cc(O)ccc3C1=C(C#N)C(=O)CC2

InChI Key InChIKey=ZBWHGLHMTURFIN-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50185865   

TargetEstrogen receptor beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185865(9a-butyl-7-hydroxy-3-oxo-2,3,9,9a-tetrahydro-1H-fl...)
Affinity DataEC50:  5nMAssay Description:Activity at human ERbeta transfected in HEK293 cells assessed as transactivation of alkaline phosphatase reporter geneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185865(9a-butyl-7-hydroxy-3-oxo-2,3,9,9a-tetrahydro-1H-fl...)
Affinity DataIC50: 38nMAssay Description:Binding affinity to ERbeta by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185865(9a-butyl-7-hydroxy-3-oxo-2,3,9,9a-tetrahydro-1H-fl...)
Affinity DataIC50: 1.65E+3nMAssay Description:Binding affinity to ERalpha by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed