BDBM50186082 8-ethyl-N-isopropyl-9-oxo-8,9-dihydrothiazolo[5,4-f]quinazoline-2-carboxamidine::CHEMBL208741::N-Isopropyl-8-ethyl-9-oxo-8,9-dihydrothiazolo[5,4-f]quinazoline-2-carboxamidine

SMILES CCn1cnc2ccc3nc(sc3c2c1=O)C(=N)NC(C)C

InChI Key InChIKey=JBGGTHOWDDUOMW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50186082   

LigandPNGBDBM50186082(N-Isopropyl-8-ethyl-9-oxo-8,9-dihydrothiazolo[5,4-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CDK1/cyclinB in presence of 15 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50186082(N-Isopropyl-8-ethyl-9-oxo-8,9-dihydrothiazolo[5,4-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CDK1/cyclinBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 alpha(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50186082(N-Isopropyl-8-ethyl-9-oxo-8,9-dihydrothiazolo[5,4-...)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of GSK3alpha/betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed