BDBM50186375 CHEMBL210540::N-(5-(2-(cyclohexyloxy)-6-methylpyrimidin-4-yl)thiazol-2-yl)-5-((4-methylpiperazin-1-yl)methyl)pyrazin-2-amine

SMILES CN1CCN(Cc2cnc(Nc3ncc(s3)-c3cc(C)nc(OC4CCCCC4)n3)cn2)CC1

InChI Key InChIKey=DLIDUXYWQPLFEM-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50186375   

TargetCyclin-dependent kinase 7(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50186375(N-(5-(2-(cyclohexyloxy)-6-methylpyrimidin-4-yl)thi...)
Affinity DataIC50: 530nMAssay Description:Inhibition of CDK7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 6(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50186375(N-(5-(2-(cyclohexyloxy)-6-methylpyrimidin-4-yl)thi...)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of CDK6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50186375(N-(5-(2-(cyclohexyloxy)-6-methylpyrimidin-4-yl)thi...)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50186375(N-(5-(2-(cyclohexyloxy)-6-methylpyrimidin-4-yl)thi...)
Affinity DataIC50: 600nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50186375(N-(5-(2-(cyclohexyloxy)-6-methylpyrimidin-4-yl)thi...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50186375(N-(5-(2-(cyclohexyloxy)-6-methylpyrimidin-4-yl)thi...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of CDK5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50186375(N-(5-(2-(cyclohexyloxy)-6-methylpyrimidin-4-yl)thi...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of CDK9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed