BDBM50186376 CHEMBL427045::N-(5-(2-(cyclohexyloxy)-6-methylpyrimidin-4-yl)thiazol-2-yl)pyridin-2-amine

SMILES Cc1cc(nc(OC2CCCCC2)n1)-c1cnc(Nc2ccccn2)s1

InChI Key InChIKey=YEZLWBMZTQEIQF-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50186376   

TargetCyclin-dependent kinase 2(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50186376(N-(5-(2-(cyclohexyloxy)-6-methylpyrimidin-4-yl)thi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50186376(N-(5-(2-(cyclohexyloxy)-6-methylpyrimidin-4-yl)thi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50186376(N-(5-(2-(cyclohexyloxy)-6-methylpyrimidin-4-yl)thi...)
Affinity DataIC50: 34nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 7(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50186376(N-(5-(2-(cyclohexyloxy)-6-methylpyrimidin-4-yl)thi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50186376(N-(5-(2-(cyclohexyloxy)-6-methylpyrimidin-4-yl)thi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50186376(N-(5-(2-(cyclohexyloxy)-6-methylpyrimidin-4-yl)thi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed