BDBM50186437 CHEMBL377311::N-(4-aminobutyl)-2-(3-(4-hydroxyphenyl)-4,5-dihydroisoxazol-5-yl)acetamide::US8618147, 9

SMILES NCCCCNC(=O)CC1CC(=NO1)c1ccc(O)cc1

InChI Key InChIKey=DXZLYCSOKUOUTP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50186437   

TargetMacrophage migration inhibitory factor(Mouse)
The Feinstein Institute For Medical Research

US Patent
LigandPNGBDBM50186437(US8618147, 9 | CHEMBL377311 | N-(4-aminobutyl)-2-(...)
Affinity DataIC50: 1.00E+5nMpH: 7.2 T: 2°CAssay Description:MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2014
Entry Details
Go to US Patent

TargetMacrophage migration inhibitory factor(Human)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50186437(US8618147, 9 | CHEMBL377311 | N-(4-aminobutyl)-2-(...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MIF tautomerase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed