BDBM50186783 4'-[1-(1-benzyl-piperidin-4-yl)-3-(5-fluoro-6-trifluoromethyl-1H-benzoimidazol-2-yl)-propyl]-biphenyl-3-carbonitrile::CHEMBL211335

SMILES Fc1cc2[nH]c(CCC(C3CCN(Cc4ccccc4)CC3)c3ccc(cc3)-c3cccc(c3)C#N)nc2cc1C(F)(F)F

InChI Key InChIKey=XVDPLVQVGSHOLM-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50186783   

TargetMelanin-concentrating hormone receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50186783(4'-[1-(1-benzyl-piperidin-4-yl)-3-(5-fluoro-6-trif...)
Affinity DataKi:  92nMAssay Description:Binding affinity at human MCHR1 assessed as inhibition of MCH-mediated calcium ion influx by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50186783(4'-[1-(1-benzyl-piperidin-4-yl)-3-(5-fluoro-6-trif...)
Affinity DataKi: >3.00E+3nMAssay Description:Binding affinity at human MCHR2 assessed as inhibition of MCH-mediated calcium ion influx by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed