BDBM50186785 2-{[4-(3'-cyano-biphenyl-4-yl)-1-cyclopentyl-piperidin-4-yl]-methyl-amino}-N-(4-fluoro-3-trifluoromethyl-phenyl)-acetamide::CHEMBL377738

SMILES CN(CC(=O)Nc1ccc(F)c(c1)C(F)(F)F)C1(CCN(CC1)C1CCCC1)c1ccc(cc1)-c1cccc(c1)C#N

InChI Key InChIKey=MSJFHHISKJEGQB-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50186785   

TargetMelanin-concentrating hormone receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50186785(2-{[4-(3'-cyano-biphenyl-4-yl)-1-cyclopentyl-piper...)
Affinity DataKi:  18nMAssay Description:Binding affinity at human MCHR1 assessed as inhibition of MCH-mediated calcium ion influx by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50186785(2-{[4-(3'-cyano-biphenyl-4-yl)-1-cyclopentyl-piper...)
Affinity DataKi: >3.00E+3nMAssay Description:Binding affinity at human MCHR2 assessed as inhibition of MCH-mediated calcium ion influx by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed