BDBM50186812 4-(3'-cyano-biphenyl-4-yl)-4-[2-(3,4-difluoro-phenylcarbamoyl)-ethyl]-piperidine-1-carboxylic acid benzylester::CHEMBL211058

SMILES Fc1ccc(NC(=O)CCC2(CCN(CC2)C(=O)OCc2ccccc2)c2ccc(cc2)-c2cccc(c2)C#N)cc1F

InChI Key InChIKey=XWOZVUBFZUQYOA-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50186812   

TargetMelanin-concentrating hormone receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50186812(4-(3'-cyano-biphenyl-4-yl)-4-[2-(3,4-difluoro-phen...)
Affinity DataKi:  51nMAssay Description:Binding affinity at human MCHR1 assessed as inhibition of MCH-mediated calcium ion influx by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50186812(4-(3'-cyano-biphenyl-4-yl)-4-[2-(3,4-difluoro-phen...)
Affinity DataKi: >3.00E+3nMAssay Description:Binding affinity at human MCHR2 assessed as inhibition of MCH-mediated calcium ion influx by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed