BDBM50186825 5-{4-[(1-cyclopropylmethyl-piperidin-4-ylidene)-(5-fluoro-6-trifluoromethyl-1H-benzoimidazol-2-yl)-methyl]-phenyl}-6-hydroxy-nicotinonitrile::CHEMBL209590

SMILES Fc1cc2[nH]c(nc2cc1C(F)(F)F)C(=C1CCN(CC2CC2)CC1)c1ccc(cc1)-c1cc(c[nH]c1=O)C#N

InChI Key InChIKey=IMMIYXMQLAQCFS-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50186825   

TargetMelanin-concentrating hormone receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50186825(5-{4-[(1-cyclopropylmethyl-piperidin-4-ylidene)-(5...)
Affinity DataKi:  99nMAssay Description:Binding affinity to human MCHR1 assessed as inhibition of MCH-mediated calcium ion influx by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed