BDBM50186851 4'-[1-(5-fluoro-6-trifluoromethyl-1H-benzoimidazol-2-yl)-6-(propane-2-sulfonyl)-6-aza-spiro[2.5]oct-1-yl]-biphenyl-3-carbonitrile::CHEMBL208688

SMILES CC(C)S(=O)(=O)N1CCC2(CC2(c2nc3cc(c(F)cc3[nH]2)C(F)(F)F)c2ccc(cc2)-c2cccc(c2)C#N)CC1

InChI Key InChIKey=HKIMHHCVNCTDQD-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50186851   

TargetMelanin-concentrating hormone receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50186851(4'-[1-(5-fluoro-6-trifluoromethyl-1H-benzoimidazol...)
Affinity DataKi:  67nMAssay Description:Binding affinity to human MCHR1 assessed as inhibition of MCH-mediated calcium ion influx by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed