BDBM50187448 1-(6-bromo-5-methoxypyridin-3-yl)piperazine::CHEMBL382985

SMILES COc1cc(cnc1Br)N1CCNCC1

InChI Key InChIKey=CHQFGLQUINKUJZ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50187448   

TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50187448(1-(6-bromo-5-methoxypyridin-3-yl)piperazine | CHEM...)
Affinity DataIC50: 182nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50187448(1-(6-bromo-5-methoxypyridin-3-yl)piperazine | CHEM...)
Affinity DataEC50:  1.70E+4nMAssay Description:Agonist activity at human alpha4beta2 nAChR expressed in HEK293 cells assessed as intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
LigandPNGBDBM50187448(1-(6-bromo-5-methoxypyridin-3-yl)piperazine | CHEM...)
Affinity DataIC50: 180nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed