BDBM50187449 (+/-)-3-chloro-5-(piperidin-3-yloxy)-pyridine::3-chloro-5-(piperidin-3-yloxy)pyridine::CHEMBL208754

SMILES Clc1cncc(OC2CCCNC2)c1

InChI Key InChIKey=CREADRXFMNTHBO-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50187449   

TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50187449(3-chloro-5-(piperidin-3-yloxy)pyridine | (+/-)-3-c...)
Affinity DataIC50: 240nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50187449(3-chloro-5-(piperidin-3-yloxy)pyridine | (+/-)-3-c...)
Affinity DataEC50:  1.41E+3nMAssay Description:Agonist activity at human alpha4beta2 nAChR expressed in HEK293 cells assessed as intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
LigandPNGBDBM50187449(3-chloro-5-(piperidin-3-yloxy)pyridine | (+/-)-3-c...)
Affinity DataIC50: 240nMAssay Description:Inhibition of [3H]cytisine binding to alpha4beta2 nACHR in Wistar rat cerebral cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed