BDBM50187632 4-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide::CHEMBL378434

SMILES O=C(Nc1cc(nn1-c1ccccc1)-c1ccccc1)c1ccc(cc1)C#N

InChI Key InChIKey=YOQRDFGCIVWWAO-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50187632   

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50187632(4-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide ...)
Affinity DataEC50:  75nMAssay Description:Activity at mGluR5 assessed as potentiation of glutamate-induced calcium flux in rat astrocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50187632(4-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide ...)
Affinity DataKi:  1.56E+3nMAssay Description:Displacement of [3H]methoxyPEPy from rat mGluR5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed