BDBM50187637 CHEMBL382766::N-(1-phenyl-3-(2-chlorophenyl)-1H-pyrazol-3-yl)benzamide

SMILES Clc1ccccc1-c1cc(NC(=O)c2ccccc2)n(n1)-c1ccccc1

InChI Key InChIKey=OMWDAJQIBZZXPV-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50187637   

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50187637(N-(1-phenyl-3-(2-chlorophenyl)-1H-pyrazol-3-yl)ben...)
Affinity DataEC50:  2.29E+3nMAssay Description:Activity at mGluR5 assessed as potentiation of glutamate-induced calcium flux in rat astrocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50187637(N-(1-phenyl-3-(2-chlorophenyl)-1H-pyrazol-3-yl)ben...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]methoxyPEPy from rat mGluR5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed