BDBM50187790 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-hexanoyl-N-hydroxypiperidine-4-carboxamide::CHEMBL212205

SMILES CCCCCC(=O)N1CCC(CS(=O)(=O)c2ccc(OCC#CC)cc2)(CC1)C(=O)NO

InChI Key InChIKey=ZUMRSIZQUOZFGG-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50187790   

TargetMatrix metalloproteinase-14(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187790(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-hexa...)
Affinity DataIC50: 4.85E+3nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187790(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-hexa...)
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50187790(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-hexa...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187790(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-hexa...)
Affinity DataIC50: 553nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187790(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-hexa...)
Affinity DataIC50: 5.46E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed