BDBM50187796 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-butyryl-N-hydroxypiperidine-4-carboxamide::CHEMBL211487

SMILES CCCC(=O)N1CCC(CS(=O)(=O)c2ccc(OCC#CC)cc2)(CC1)C(=O)NO

InChI Key InChIKey=MTSOZTJGECJILJ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50187796   

TargetMatrix metalloproteinase-14(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187796(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-buty...)
Affinity DataIC50: 725nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187796(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-buty...)
Affinity DataIC50: 24nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187796(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-buty...)
Affinity DataIC50: 49nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50187796(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-buty...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187796(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-buty...)
Affinity DataIC50: 4.15E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed