BDBM50188021 2-ethoxy-3-(1-((5-methyl-2-(4-(trifluoromethyl)phenyl)oxazol-4-yl)methyl)-1H-indol-5-yl)propanoic acid::CHEMBL213675

SMILES CCOC(Cc1ccc2n(Cc3nc(oc3C)-c3ccc(cc3)C(F)(F)F)ccc2c1)C(O)=O

InChI Key InChIKey=ZYXIXLCLHFATLN-UHFFFAOYSA-N

Data  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50188021   

TargetPeroxisome proliferator-activated receptor alpha(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188021(2-ethoxy-3-(1-((5-methyl-2-(4-(trifluoromethyl)phe...)
Affinity DataIC50: 70nMAssay Description:Binding affinity to PPARalpha by radio ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188021(2-ethoxy-3-(1-((5-methyl-2-(4-(trifluoromethyl)phe...)
Affinity DataEC50:  1.70E+3nMAssay Description:Activity at PPARdelta by luciferase reporter gene transactivation assay relative to GW 501516More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188021(2-ethoxy-3-(1-((5-methyl-2-(4-(trifluoromethyl)phe...)
Affinity DataEC50:  170nMAssay Description:Activity at PPARalpha by luciferase reporter gene transactivation assay relative to farglitazarMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188021(2-ethoxy-3-(1-((5-methyl-2-(4-(trifluoromethyl)phe...)
Affinity DataEC50:  470nMAssay Description:Activity at PPARgamma by luciferase reporter gene transactivation assay relative to edaglitazoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188021(2-ethoxy-3-(1-((5-methyl-2-(4-(trifluoromethyl)phe...)
Affinity DataIC50: 321nMAssay Description:Binding affinity to PPARgamma by radio ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed