BDBM50188039 2-isopropoxy-3-(1-((5-methyl-2-(4-(trifluoromethyl)phenyl)oxazol-4-yl)methyl)-1H-indol-5-yl)propanoic acid::CHEMBL210017

SMILES CC(C)OC(Cc1ccc2n(Cc3nc(oc3C)-c3ccc(cc3)C(F)(F)F)ccc2c1)C(O)=O

InChI Key InChIKey=PABWXIBCXIQVPC-UHFFFAOYSA-N

Data  3 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50188039   

TargetPeroxisome proliferator-activated receptor gamma(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188039(2-isopropoxy-3-(1-((5-methyl-2-(4-(trifluoromethyl...)
Affinity DataIC50: 139nMAssay Description:Binding affinity to PPARgamma by radio ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188039(2-isopropoxy-3-(1-((5-methyl-2-(4-(trifluoromethyl...)
Affinity DataEC50:  2.20E+3nMAssay Description:Activity at PPARdelta by luciferase reporter gene transactivation assay relative to GW 501516More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188039(2-isopropoxy-3-(1-((5-methyl-2-(4-(trifluoromethyl...)
Affinity DataIC50: 61nMAssay Description:Binding affinity to PPARalpha by radio ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188039(2-isopropoxy-3-(1-((5-methyl-2-(4-(trifluoromethyl...)
Affinity DataEC50:  20nMAssay Description:Activity at PPARalpha by luciferase reporter gene transactivation assay relative to farglitazarMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188039(2-isopropoxy-3-(1-((5-methyl-2-(4-(trifluoromethyl...)
Affinity DataEC50:  160nMAssay Description:Activity at PPARgamma by luciferase reporter gene transactivation assay relative to edaglitazoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188039(2-isopropoxy-3-(1-((5-methyl-2-(4-(trifluoromethyl...)
Affinity DataIC50: 892nMAssay Description:Binding affinity to PPARdelta by radio ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed