BDBM50188365 8-[2-(3-fluoro-phenyl)-2-hydroxy-cyclohexyl]-4-phenyl-2,8-diaza-spiro[4.5]decan-1-one::CHEMBL386444

SMILES OC1(CCCCC1N1CCC2(CC1)C(CNC2=O)c1ccccc1)c1cccc(F)c1

InChI Key InChIKey=VTESATXDAMBSLY-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50188365   

TargetSodium- and chloride-dependent glycine transporter 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188365(8-[2-(3-fluoro-phenyl)-2-hydroxy-cyclohexyl]-4-phe...)
Affinity DataEC50:  158nMAssay Description:Inhibition of [3H]glycine uptake at human GlyT1 by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed