BDBM50188366 8-[2-(3-chloro-phenyl)-2-hydroxy-cyclohexyl]-4-(4-fluoro-phenyl)-2,8-diaza-spiro[4.5]decan-1-one::CHEMBL386977

SMILES OC1(CCCCC1N1CCC2(CC1)C(CNC2=O)c1ccc(F)cc1)c1cccc(Cl)c1

InChI Key InChIKey=WWZNPMCMNQTFRR-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50188366   

TargetSodium- and chloride-dependent glycine transporter 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188366(8-[2-(3-chloro-phenyl)-2-hydroxy-cyclohexyl]-4-(4-...)
Affinity DataEC50:  118nMAssay Description:Inhibition of [3H]glycine uptake at human GlyT1 by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed