BDBM50188882 CHEMBL384202::rac-4-phenyl-8-[1-(4-trifluoromethoxy-phenyl)-cyclohexyl]-2,8-diaza-spiro[4.5]decan-1-one

SMILES FC(F)(F)Oc1ccc(cc1)C1(CCCCC1)N1CCC2(CC1)C(CNC2=O)c1ccccc1

InChI Key InChIKey=XOBVYGFLFIMBKT-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50188882   

TargetSodium- and chloride-dependent glycine transporter 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188882(rac-4-phenyl-8-[1-(4-trifluoromethoxy-phenyl)-cycl...)
Affinity DataEC50:  4.56E+3nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed