BDBM50188885 CHEMBL209947::rac-8-[1-(4-fluoro-phenyl)-cyclohexyl]-4-(4-trifluoromethyl-phenyl)-2,8-diaza-spiro[4.5]decan-1-one

SMILES Fc1ccc(cc1)C1(CCCCC1)N1CCC2(CC1)C(CNC2=O)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=FTOXYKIABNPIDL-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50188885   

TargetSodium- and chloride-dependent glycine transporter 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188885(rac-8-[1-(4-fluoro-phenyl)-cyclohexyl]-4-(4-triflu...)
Affinity DataEC50:  433nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed