BDBM50189121 CHEMBL214023::N-(4-(3-fluorobenzyloxy)-3-(trifluoromethyl)phenyl)-6-(5-((2-(pyridin-2-ylsulfonyl)ethylamino)methyl)furan-2-yl)quinazolin-4-amine

SMILES Fc1cccc(COc2ccc(Nc3ncnc4ccc(cc34)-c3ccc(CNCCS(=O)(=O)c4ccccn4)o3)cc2C(F)(F)F)c1

InChI Key InChIKey=NXQXZOZVAHCESP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50189121   

TargetEpidermal growth factor receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50189121(N-(4-(3-fluorobenzyloxy)-3-(trifluoromethyl)phenyl...)
Affinity DataIC50: 19nMAssay Description:Inhibition of ErbB1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50189121(N-(4-(3-fluorobenzyloxy)-3-(trifluoromethyl)phenyl...)
Affinity DataIC50: 30nMAssay Description:Inhibition of ErbB2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed