BDBM50189122 CHEMBL377250::[4-(3-fluoro-benzyloxy)-3-trifluoromethyl-phenyl]-{6-[5-(1-oxo-1lambda*4*-thiomorpholin-4-ylmethyl)-furan-2-yl]-quinazolin-4-yl}-amine

SMILES Fc1cccc(COc2ccc(Nc3ncnc4ccc(cc34)-c3ccc(CN4CCS(=O)CC4)o3)cc2C(F)(F)F)c1

InChI Key InChIKey=JZWRJCKVZCYRLF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50189122   

TargetEpidermal growth factor receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50189122([4-(3-fluoro-benzyloxy)-3-trifluoromethyl-phenyl]-...)
Affinity DataIC50: 89nMAssay Description:Inhibition of ErbB1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50189122([4-(3-fluoro-benzyloxy)-3-trifluoromethyl-phenyl]-...)
Affinity DataIC50: 141nMAssay Description:Inhibition of ErbB2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed