BDBM50189183 (S)-1-(4-(2-(1-amino-3-methylbutyl)-6-fluorophenyl)piperazin-1-yl)-3-(2,4-dichlorophenyl)propan-1-one::CHEMBL213380

SMILES CC(C)C[C@H](N)c1cccc(F)c1N1CCN(CC1)C(=O)CCc1ccc(Cl)cc1Cl

InChI Key InChIKey=VIFYVTWZHBRVAT-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50189183   

TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50189183((S)-1-(4-(2-(1-amino-3-methylbutyl)-6-fluorophenyl...)
Affinity DataKi:  110nMAssay Description:Activity at MC4R assessed as inhibition of alpha-MSH-stimulated cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50189183((S)-1-(4-(2-(1-amino-3-methylbutyl)-6-fluorophenyl...)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [125I]NDP-MSH from human MC5R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50189183((S)-1-(4-(2-(1-amino-3-methylbutyl)-6-fluorophenyl...)
Affinity DataKi:  1.40E+3nMAssay Description:Displacement of [125I]NDP-MSH from human MC3R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed