BDBM50189210 (S)-2-amino-N-(1-(2-(4-(3-(2,4-dichlorophenyl)propanoyl)piperazin-1-yl)-5-(trifluoromethyl)phenyl)-3-methylbutyl)acetamide::CHEMBL211564::N-(1S-[2-{4-[3-(4-chlorophenyl)propionyl]-1-piperazinyl}-5-(trifluoromethyl)phenyl]-3-methylbutyl)-2-aminoacetamide

SMILES CC(C)C[C@H](NC(=O)CN)c1cc(ccc1N1CCN(CC1)C(=O)CCc1ccc(Cl)cc1Cl)C(F)(F)F

InChI Key InChIKey=JKCHNCUBXBYAJL-UHFFFAOYSA-N

Data  6 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50189210   

TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50189210(N-(1S-[2-{4-[3-(4-chlorophenyl)propionyl]-1-pipera...)
Affinity DataKi:  19nMAssay Description:Displacement of [125I]NDPMSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50189210(N-(1S-[2-{4-[3-(4-chlorophenyl)propionyl]-1-pipera...)
Affinity DataKi:  19nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50189210(N-(1S-[2-{4-[3-(4-chlorophenyl)propionyl]-1-pipera...)
Affinity DataKi:  500nMAssay Description:Displacement of [125I]NDP-MSH from human MC5R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50189210(N-(1S-[2-{4-[3-(4-chlorophenyl)propionyl]-1-pipera...)
Affinity DataKi:  500nMAssay Description:Displacement of [125I]NDPMSH from human MC5R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50189210(N-(1S-[2-{4-[3-(4-chlorophenyl)propionyl]-1-pipera...)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [125I]NDP-MSH from human MC3R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50189210(N-(1S-[2-{4-[3-(4-chlorophenyl)propionyl]-1-pipera...)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [125I]NDPMSH from human MC3R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50189210(N-(1S-[2-{4-[3-(4-chlorophenyl)propionyl]-1-pipera...)
Affinity DataIC50: 1.30E+3nMAssay Description:Antagonist activity at human MC4R expressed in HEK293 cells assessed as inhibition of alpha-MSH-stimulated cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50189210(N-(1S-[2-{4-[3-(4-chlorophenyl)propionyl]-1-pipera...)
Affinity DataIC50: 1.30E+3nMAssay Description:Activity at MC4R assessed as inhibition of alpha-MSH-stimulated cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed