BDBM50189309 CHEMBL9126

SMILES NC(=N)c1ccc(cc1)N1CCN(CC1)c1ccc(cc1)C(N)=N

InChI Key InChIKey=GFDIGDWACCJVOI-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50189309   

TargetTrypsin(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189309(CHEMBL9126)
Affinity DataKi:  513nMAssay Description:Inhibition of human trypsin using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189309(CHEMBL9126)
Affinity DataKi:  719nMAssay Description:Inhibition of human matriptase using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed
TargetTransmembrane protease serine 6(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189309(CHEMBL9126)
Affinity DataKi:  1.16E+3nMAssay Description:Inhibition of human matriptase-2 transfected in HEK cells using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed
TargetProthrombin(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189309(CHEMBL9126)
Affinity DataKi:  1.01E+4nMAssay Description:Inhibition of human thrombin using Cbz-Gly-Gly-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed
TargetCoagulation factor X(Bovine)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50189309(CHEMBL9126)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibition of bovine factor 10a using Boc-Ile-Glu-Gly-Arg-AMC as substrate after 20 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2017
Entry Details Article
PubMed