BDBM50189317 CHEMBL3827432

SMILES CN(CCCOc1ccc2ccc(=O)oc2c1)Cc1cccc(OC(=O)NCCCCCCc2ccccc2)c1

InChI Key InChIKey=CQTFNVLDNHGYMC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50189317   

TargetAcetylcholinesterase(Human)
Alma Mater Studiorum-University of Bologna

Curated by ChEMBL
LigandPNGBDBM50189317(CHEMBL3827432)
Affinity DataIC50: 109nMAssay Description:Inhibition of recombinant human AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate preincubated for 120 mins followed by subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2017
Entry Details Article
PubMed
TargetCholinesterase(Human)
Alma Mater Studiorum-University of Bologna

Curated by ChEMBL
LigandPNGBDBM50189317(CHEMBL3827432)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human serum BuChE using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition by Ellman's meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2017
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Alma Mater Studiorum-University of Bologna

Curated by ChEMBL
LigandPNGBDBM50189317(CHEMBL3827432)
Affinity DataIC50: 1.79E+3nMAssay Description:Inhibition of FAAH in rat brain membrane using N-arachidonoyl-[14C]-ethanolamine as substrate incubated for 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2017
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Alma Mater Studiorum-University of Bologna

Curated by ChEMBL
LigandPNGBDBM50189317(CHEMBL3827432)
Affinity DataIC50: 530nMAssay Description:Inhibition of FAAH in rat brain membrane using N-arachidonoyl-[14C]-ethanolamine as substrate preincubated for 20 mins followed by substrate addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2017
Entry Details Article
PubMed