BDBM50189365 CHEMBL212345::N'-(2-(((3S)-2-hydroxy-5-oxo-tetrahydrofuran-3-yl)carbamoyl)-2,3-dihydro-1H-indene-2-carbonyl)-2-naphthohydrazide

SMILES OC1OC(=O)C[C@@H]1NC(=O)C1(Cc2ccccc2C1)C(=O)NNC(=O)c1ccc2ccccc2c1

InChI Key InChIKey=WGXRRPITZPAKDK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50189365   

TargetCaspase-1(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189365(N'-(2-(((3S)-2-hydroxy-5-oxo-tetrahydrofuran-3-yl)...)
Affinity DataIC50: 30nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-8(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189365(N'-(2-(((3S)-2-hydroxy-5-oxo-tetrahydrofuran-3-yl)...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of caspase8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189365(N'-(2-(((3S)-2-hydroxy-5-oxo-tetrahydrofuran-3-yl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of caspase3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed