BDBM50189366 CHEMBL214044::N'-(1-(((3S)-2-hydroxy-5-oxo-tetrahydrofuran-3-yl)carbamoyl)cyclohexanecarbonyl)-2,6-dimethoxybenzohydrazide

SMILES COc1cccc(OC)c1C(=O)NNC(=O)C1(CCCCC1)C(=O)N[C@H]1CC(=O)OC1O

InChI Key InChIKey=WUQPWSWGFKLLRA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50189366   

TargetCaspase-8(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189366(N'-(1-(((3S)-2-hydroxy-5-oxo-tetrahydrofuran-3-yl)...)
Affinity DataIC50: 300nMAssay Description:Inhibition of caspase8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189366(N'-(1-(((3S)-2-hydroxy-5-oxo-tetrahydrofuran-3-yl)...)
Affinity DataIC50: 700nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189366(N'-(1-(((3S)-2-hydroxy-5-oxo-tetrahydrofuran-3-yl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of caspase3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed