BDBM50189375 CHEMBL212981::N-[(3S)-2-hydroxy-5-oxotetrahydrofuran-3-yl]-1-{[2-(1-naphthoyl)hydrazino]carbonyl}cyclopentane carboxamide

SMILES OC1OC(=O)C[C@@H]1NC(=O)C1(CCCC1)C(=O)NNC(=O)c1cccc2ccccc12

InChI Key InChIKey=GFJVEQNTNYTSIH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50189375   

TargetCaspase-1(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189375(N-[(3S)-2-hydroxy-5-oxotetrahydrofuran-3-yl]-1-{[2...)
Affinity DataIC50: 40nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-8(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189375(N-[(3S)-2-hydroxy-5-oxotetrahydrofuran-3-yl]-1-{[2...)
Affinity DataIC50: 90nMAssay Description:Inhibition of caspase8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189375(N-[(3S)-2-hydroxy-5-oxotetrahydrofuran-3-yl]-1-{[2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of caspase3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed