BDBM50189812 CHEMBL212458::N-benzoyl-N-[2-(4-methoxy-phenyl)-1-oxo-1,2-dihydro-[1,2,4]triazolo[4,3-a]quinoxalin-4-yl]-benzamide

SMILES COc1ccc(cc1)-n1nc2c(nc3ccccc3n2c1=O)N(C(=O)c1ccccc1)C(=O)c1ccccc1

InChI Key InChIKey=GTRCYAYRRCMTDF-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50189812   

TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50189812(N-benzoyl-N-[2-(4-methoxy-phenyl)-1-oxo-1,2-dihydr...)
Affinity DataIC50: 31.8nMAssay Description:Antagonist activity against Cl-IB-MECA inhibited cAMP level in CHO cells transfected with human A3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50189812(N-benzoyl-N-[2-(4-methoxy-phenyl)-1-oxo-1,2-dihydr...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NECA-stimulated cAMP level in CHO cells transfected with human adenosine A2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50189812(N-benzoyl-N-[2-(4-methoxy-phenyl)-1-oxo-1,2-dihydr...)
Affinity DataKi:  3.29nMAssay Description:Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Bovine)
Università

Curated by ChEMBL
LigandPNGBDBM50189812(N-benzoyl-N-[2-(4-methoxy-phenyl)-1-oxo-1,2-dihydr...)
Affinity DataKi:  175nMAssay Description:Displacement of [3H]DPCPX from adenosine A1 receptor in bovine brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50189812(N-benzoyl-N-[2-(4-methoxy-phenyl)-1-oxo-1,2-dihydr...)
Affinity DataKi:  6.57E+3nMAssay Description:Displacement of [3H]CGS 21680 from adenosine A2A receptor in bovine striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed