BDBM50189931 CHEMBL3828577::US10618914, Compound 9a::US11111253, Compound 9a

SMILES C1Cc2n[nH]c(c2C1)-c1nnc2SCC(=Nn12)c1ccncc1

InChI Key InChIKey=LGMXKAFOZXXFQI-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50189931   

TargetSignal transducer and activator of transcription 1-alpha/beta(Human)
University of Pittsburgh

US Patent
LigandPNGBDBM50189931(CHEMBL3828577 | US10618914, Compound 9a | US111112...)
Affinity DataIC50: 5.00E+4nMAssay Description:Compound samples (in 3-5 mg quantities) were evaluated in a variety of assays. All compound submissions were fully characterized (1H, 13C, IR, FIRMS)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetSignal transducer and activator of transcription 1-alpha/beta(Human)
University of Pittsburgh

US Patent
LigandPNGBDBM50189931(CHEMBL3828577 | US10618914, Compound 9a | US111112...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of IFNgamma-induced STAT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2017
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 1-alpha/beta(Human)
University of Pittsburgh

US Patent
LigandPNGBDBM50189931(CHEMBL3828577 | US10618914, Compound 9a | US111112...)
Affinity DataIC50: 5.00E+4nMAssay Description:Compound samples (in 3-5 mg quantities) were evaluated in a variety of assays. All compound submissions were fully characterized (1H, 13C, IR, HRMS),...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetSignal transducer and activator of transcription 3(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50189931(CHEMBL3828577 | US10618914, Compound 9a | US111112...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of IL6-induced STAT3 in human CAL33 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2017
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50189931(CHEMBL3828577 | US10618914, Compound 9a | US111112...)
Affinity DataIC50: 5.00E+4nMAssay Description:Compound samples (in 3-5 mg quantities) were evaluated in a variety of assays. All compound submissions were fully characterized (1H, 13C, IR, HRMS),...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetSignal transducer and activator of transcription 3(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50189931(CHEMBL3828577 | US10618914, Compound 9a | US111112...)
Affinity DataIC50: 5.00E+4nMAssay Description:Compound samples (in 3-5 mg quantities) were evaluated in a variety of assays. All compound submissions were fully characterized (1H, 13C, IR, FIRMS)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent