BDBM50190464 1-(3,5-diamino-2-chloropyrazine-6-carbonyl)-3-(5-(4-hydroxyphenyl)pentyl)guanidine::CHEMBL211221

SMILES NC(NC(=O)c1nc(Cl)c(N)nc1N)=NCCCCCc1ccc(O)cc1

InChI Key InChIKey=AFHJQBXQWMBTAO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50190464   

TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190464(1-(3,5-diamino-2-chloropyrazine-6-carbonyl)-3-(5-(...)
Affinity DataIC50: 64nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed