BDBM50190807 CHEMBL3915306

SMILES Clc1ccc(COc2ccc(Nc3ncnc4cc5oc(=O)n(CCOC(=O)CBr)c5cc34)cc2)cc1

InChI Key InChIKey=MLUJQJKMFNMWBV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50190807   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50190807(CHEMBL3915306)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of His-tagged human HER2 (676 to 1255 residues) expressed in baculovirus after 1 hr by Z-lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2018
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50190807(CHEMBL3915306)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of GST-tagged wild type recombinant human EGFR (668 to 1210 residues) expressed in baculovirus after 1 hr by Z-lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2018
Entry Details Article
PubMed