BDBM50191369 17-allylamino-17-demethoxygeldanamycin hydroquinone carbamate::CHEMBL378935

SMILES CO[C@H]1C[C@H](C)Cc2c(O)c(NC(=O)C(C)=CC=C[C@H](OC)[C@@H](OC(N)=O)\C(C)=C\[C@H](C)[C@H]1O)cc1oc(=O)n(CC=C)c21

InChI Key InChIKey=OCIPHIZBUIHMJY-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50191369   

TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191369(17-allylamino-17-demethoxygeldanamycin hydroquinon...)
Affinity DataEC50:  1.05E+3nMAssay Description:Degradation of Her2 in SKBR3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191369(17-allylamino-17-demethoxygeldanamycin hydroquinon...)
Affinity DataEC50:  742nMAssay Description:Degradation of Her2 in SKOV3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191369(17-allylamino-17-demethoxygeldanamycin hydroquinon...)
Affinity DataEC50:  384nMAssay Description:Upregulation of Hsp70 in SKBR3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191369(17-allylamino-17-demethoxygeldanamycin hydroquinon...)
Affinity DataEC50:  2.28E+3nMAssay Description:Upregulation of Hsp70 in SKOV3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed