BDBM50191628 CHEMBL210656::rac-N-[3-(5-fluoro-1H-indol-3-yl)propyl]-5-methoxy-N-methylchroman-3-amine

SMILES COc1cccc2OCC(Cc12)N(C)CCCc1c[nH]c2ccc(F)cc12

InChI Key InChIKey=DVPDEYGRKNNDDO-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50191628   

TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50191628(rac-N-[3-(5-fluoro-1H-indol-3-yl)propyl]-5-methoxy...)
Affinity DataIC50: 15nMAssay Description:Inhibition of [3H]5-HT uptake at human 5-HT transporter expressed in Jar cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50191628(rac-N-[3-(5-fluoro-1H-indol-3-yl)propyl]-5-methoxy...)
Affinity DataKi:  6.80nMAssay Description:Displacement of [3H]paroxetine from 5-HT transporter in Sprague-Dawley rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50191628(rac-N-[3-(5-fluoro-1H-indol-3-yl)propyl]-5-methoxy...)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed