BDBM50191760 CHEMBL216038::N-(3-dimethylaminomethyl-quinolin-8-ylmethyl)-6-(4-fluoro-phenyl)-nicotinamide

SMILES CN(C)Cc1cnc2c(CNC(=O)c3ccc(nc3)-c3ccc(F)cc3)cccc2c1

InChI Key InChIKey=VKMCZNFXCGAVGY-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50191760   

Target5-hydroxytryptamine receptor 2C(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191760(N-(3-dimethylaminomethyl-quinolin-8-ylmethyl)-6-(4...)
Affinity DataIC50: 1.03E+4nMAssay Description:Displacement of [3H]mesulergine from 5HT2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191760(N-(3-dimethylaminomethyl-quinolin-8-ylmethyl)-6-(4...)
Affinity DataKi:  414nMAssay Description:Binding affinity to MCHR1 by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed