BDBM50191838 4-chloro-6-(4-(4-methyl-1H-imidazol-5-yl)piperidin-1-yl)-5-phenylpyrimidine::CHEMBL215928

SMILES Cc1nc[nH]c1C1CCN(CC1)c1ncnc(Cl)c1-c1ccccc1

InChI Key InChIKey=NISHIGIRWIWAAM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50191838   

TargetSodium/hydrogen exchanger 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50191838(4-chloro-6-(4-(4-methyl-1H-imidazol-5-yl)piperidin...)
Affinity DataIC50: 580nMAssay Description:Inhibition of human NHE1 expressed in Ap1 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed