BDBM50191843 2-(5-(4-fluoro-3-methylphenyl)-4-(4-(4-methyl-1H-imidazol-5-yl)piperidin-1-yl)pyrimidin-2-yl)-N-isopropylacetamide::CHEMBL214646

SMILES CC(C)NC(=O)Cc1ncc(-c2ccc(F)c(C)c2)c(n1)N1CCC(CC1)c1[nH]cnc1C

InChI Key InChIKey=LSNWZZMYCNOALY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50191843   

TargetSodium/hydrogen exchanger 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50191843(2-(5-(4-fluoro-3-methylphenyl)-4-(4-(4-methyl-1H-i...)
Affinity DataIC50: 87nMAssay Description:Inhibition of human NHE1 expressed in Ap1 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed