BDBM50191978 CHEMBL3915941

SMILES Cc1ncc(cc1NC(=O)c1cnn2cc(ccc12)-c1cnn(C)c1)C(=O)NCCN1CCCC1(C)C

InChI Key InChIKey=WUPFLUOYXIDHAV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50191978   

TargetHistamine H3 receptor(Human)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50191978(CHEMBL3915941)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of H3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2018
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50191978(CHEMBL3915941)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of M1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2018
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50191978(CHEMBL3915941)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of PDGFRalpha kinase domain (unknown origin) assessed as reduction in probe peptide substrate phosphorylation by capillary electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2018
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50191978(CHEMBL3915941)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2018
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Rat)
Novartis Institutes of Biomedical Research (Nibr)

Curated by ChEMBL
LigandPNGBDBM50191978(CHEMBL3915941)
Affinity DataIC50: 13nMAssay Description:Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2018
Entry Details Article
PubMed