BDBM50192076 1-{5-[((S)-5-chloro-indan-2-ylamino)-methyl]-1H-pyrazol-3-yl}-3-((S)-5-oxo-2,3,5,9b-tetrahydro-1H-pyrrolo[2,1-a]isoindol-9-yl)-urea::1-{5-[(5-Chloro-indan-2-ylamino)-methyl]-1H-pyrazol-3-yl}-3-(5-oxo-2,3,5,9b-tetrahydro-1H-pyrrolo[2,1-a]isoindol-9-yl)-urea::CHEMBL336242

SMILES Clc1ccc2C[C@@H](Cc2c1)NCc1cc(NC(=O)Nc2cccc3C(=O)N4CCC[C@H]4c23)[nH]n1

InChI Key InChIKey=CGHADMRBCNGDHX-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50192076   

TargetCyclin-dependent kinase 4(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192076(1-{5-[(5-Chloro-indan-2-ylamino)-methyl]-1H-pyrazo...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192076(1-{5-[(5-Chloro-indan-2-ylamino)-methyl]-1H-pyrazo...)
Affinity DataIC50: 42nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50192076(1-{5-[(5-Chloro-indan-2-ylamino)-methyl]-1H-pyrazo...)
Affinity DataIC50: 78nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50192076(1-{5-[(5-Chloro-indan-2-ylamino)-methyl]-1H-pyrazo...)
Affinity DataIC50: 120nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50192076(1-{5-[(5-Chloro-indan-2-ylamino)-methyl]-1H-pyrazo...)
Affinity DataIC50: 440nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50192076(1-{5-[(5-Chloro-indan-2-ylamino)-methyl]-1H-pyrazo...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed