BDBM50192131 CHEMBL263089::methyl 2-(ethyl(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)amino)-2-phenylbutanoate

SMILES CCN(c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)C(CC)(C(=O)OC)c1ccccc1

InChI Key InChIKey=WRDYYYJMUBDBTD-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50192131   

TargetOxysterols receptor LXR-beta(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192131(methyl 2-(ethyl(4-(1,1,1,3,3,3-hexafluoro-2-hydrox...)
Affinity DataIC50: 40nMAssay Description:Binding affinity to LXRbeta by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192131(methyl 2-(ethyl(4-(1,1,1,3,3,3-hexafluoro-2-hydrox...)
Affinity DataIC50: 50nMAssay Description:Binding affinity to LXRalpha by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192131(methyl 2-(ethyl(4-(1,1,1,3,3,3-hexafluoro-2-hydrox...)
Affinity DataEC50:  70nMAssay Description:Transactivation of LXRbeta by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192131(methyl 2-(ethyl(4-(1,1,1,3,3,3-hexafluoro-2-hydrox...)
Affinity DataEC50:  300nMAssay Description:Transactivation of LXRalpha by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed