BDBM50192142 1,1,1,3,3,3-hexafluoro-2-(4-(methyl(thiazol-4-ylmethyl)amino)phenyl)propan-2-ol::CHEMBL386174

SMILES CCN(Cc1cscn1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=DBCGQWBJSYJXSD-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50192142   

TargetOxysterols receptor LXR-beta(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192142(1,1,1,3,3,3-hexafluoro-2-(4-(methyl(thiazol-4-ylme...)
Affinity DataIC50: 50nMAssay Description:Binding affinity to LXRbeta by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192142(1,1,1,3,3,3-hexafluoro-2-(4-(methyl(thiazol-4-ylme...)
Affinity DataEC50:  200nMAssay Description:Transactivation of LXRbeta by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192142(1,1,1,3,3,3-hexafluoro-2-(4-(methyl(thiazol-4-ylme...)
Affinity DataIC50: 600nMAssay Description:Binding affinity to LXRalpha by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192142(1,1,1,3,3,3-hexafluoro-2-(4-(methyl(thiazol-4-ylme...)
Affinity DataEC50:  3.30E+3nMAssay Description:Transactivation of LXRalpha by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed