BDBM50192150 4-(2-((2-chloro-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)(ethyl)amino)-2-phenylethoxy)benzoic acid::CHEMBL386260

SMILES CCN(C(COc1ccc(cc1)C(O)=O)c1ccccc1)c1ccc(cc1Cl)C(O)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=NFIGPODJIQQYKF-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50192150   

TargetOxysterols receptor LXR-beta(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192150(4-(2-((2-chloro-4-(1,1,1,3,3,3-hexafluoro-2-hydrox...)
Affinity DataIC50: 20nMAssay Description:Binding affinity to LXRbeta by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192150(4-(2-((2-chloro-4-(1,1,1,3,3,3-hexafluoro-2-hydrox...)
Affinity DataIC50: 100nMAssay Description:Binding affinity to LXRalpha by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192150(4-(2-((2-chloro-4-(1,1,1,3,3,3-hexafluoro-2-hydrox...)
Affinity DataEC50:  1.10E+3nMAssay Description:Transactivation of LXRbeta by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192150(4-(2-((2-chloro-4-(1,1,1,3,3,3-hexafluoro-2-hydrox...)
Affinity DataEC50:  3.70E+3nMAssay Description:Transactivation of LXRalpha by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed