BDBM50192278 (2S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(4-fluorophenyl)-4-(4-phenylpiperidin-1-yl)butanamide::CHEMBL209899

SMILES Fc1ccc(cc1)[C@H](CCN1CCC(CC1)c1ccccc1)C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=TWDSSLGDUOHXCF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50192278   

TargetSubstance-P receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192278((2S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(4-fluor...)
Affinity DataIC50: 24nMAssay Description:Inhibition of NK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192278((2S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(4-fluor...)
Affinity DataIC50: 72nMAssay Description:Inhibition of CCR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192278((2S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(4-fluor...)
Affinity DataIC50: 150nMAssay Description:Inhibition of [125I]MCP1 binding to CCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed