BDBM50192657 CHEMBL3901517

SMILES Fc1ccc(cc1)C1CC(=NN1C(=O)Nc1ccccc1)c1ccc(Br)cc1

InChI Key InChIKey=VFXSQHCHKHAECA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50192657   

TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50192657(CHEMBL3901517)
Affinity DataIC50: 68nMAssay Description:Inhibition of recombinant T-type calcium channel Cav3.2 (unknown origin) expressed in HEK293 cells assessed as inhibition of CaCl2-induced calcium in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2018
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50192657(CHEMBL3901517)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant T-type calcium channel Cav1.2 (unknown origin) expressed in HEK293 cells assessed as inhibition of Kcl-induced calcium infl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2018
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50192657(CHEMBL3901517)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells assessed as potassium tail current measured at -40 mV holding potential after 3 mins by QPatch clamp a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2018
Entry Details Article
PubMed