BDBM50192813 CHEMBL3896628

SMILES Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)N2[C@H]3CC[C@@H]2C[C@@H](C3)OCCO)n1

InChI Key InChIKey=WFVZKQBDAWITHK-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50192813   

TargetTransient receptor potential cation channel subfamily V member 4(Human)
Shionogi

Curated by ChEMBL

LigandBDBM50192813(CHEMBL3896628)Copy SMILESCopy InChI

Affinity DataIC50: 6.20nMAssay Description:Antagonist activity at human TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
6/30/2018
Entry Details Article
Copy Entry DOIPubMed
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TargetTransient receptor potential cation channel subfamily V member 4(Rat)
Shionogi

Curated by ChEMBL

LigandBDBM50192813(CHEMBL3896628)Copy SMILESCopy InChI

Affinity DataIC50: 200nMAssay Description:Antagonist activity at rat TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
6/30/2018
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL