BDBM50192903 8R-hydroxylobel-9-ene::CHEMBL425617

SMILES CN1[C@@H](C[C@@H](O)c2ccccc2)CCC[C@H]1\C=C\c1ccccc1

InChI Key InChIKey=IKYXUFYHDWVXST-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50192903   

TargetSodium-dependent serotonin transporter(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50192903(8R-hydroxylobel-9-ene | CHEMBL425617)
Affinity DataKi:  44nMAssay Description:Inhibition of [3H]5-HT uptake at SERT in rat hippocampal synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50192903(8R-hydroxylobel-9-ene | CHEMBL425617)
Affinity DataKi:  44nMAssay Description:Inhibition of [3H]DA uptake at DAT in rat brain striatal synaptosomes by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50192903(8R-hydroxylobel-9-ene | CHEMBL425617)
Affinity DataKi:  860nMAssay Description:Inhibition of [3H]DA uptake at DAT in rat striatal synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50192903(8R-hydroxylobel-9-ene | CHEMBL425617)
Affinity DataKi:  860nMAssay Description:Inhibition of [3H]5HT uptake at SERT in rat brain hippocampal synaptosomes by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50192903(8R-hydroxylobel-9-ene | CHEMBL425617)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of [3H]MLA binding to alpha-7 nAChR in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50192903(8R-hydroxylobel-9-ene | CHEMBL425617)
Affinity DataKi:  4.19E+3nMAssay Description:Inhibition of [3H]NIC binding to alpha-4-beta-2 nAChR in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSynaptic vesicular amine transporter(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50192903(8R-hydroxylobel-9-ene | CHEMBL425617)
Affinity DataKi:  5.16E+3nMAssay Description:Inhibition of [3H]DTBZ binding to VMAT2 in rat synaptic vesicle membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSynaptic vesicular amine transporter(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50192903(8R-hydroxylobel-9-ene | CHEMBL425617)
Affinity DataKi:  5.16E+3nMAssay Description:Binding affinity to VMAT2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed